Cholinergic excitation from the pedunculopontine tegmental nucleus to the dentate nucleus in the rat
详细信息 查看全文
- 作者：F. Vitalea ; &dagger ; ; C. Matteia ; &dagger ; ; A. Capozzoa ; I. Pietrantonia ; P. Mazzoneb ; E. Scarnatia ; scarnati@univaq.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：ACh ; acetylcholine ; DA ; dopamine ; DBS ; deep brain stimulation ; GLU ; glutamate ; NADPH-diaphorase ; nicotinamide adenine dinucleotide phosphate-diaphorase ; PD ; Parkinson&rsquo ; s disease ; PETH ; peri-event time histogram ; PPTg ; pedunculopontine tegmental nucleus ; STN ; subthalamic nucleus
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：11 March 2016
- 年：2016
- 卷：317
- 期：Complete
- 页码：12-22
- 全文大小：971 K
文摘
- •
Stimulation of the pedunculopontine tegmental nucleus excited cerebellar nuclei.
- •
The excitation was mediated by neuronal cell bodies in the stimulated site.
- •
Iontophoretic application of acetylcholine antagonists blocked the evoked response.
- •
These data may help to explain deep-brain stimulation effects in motor disorders.