Quantitative hepatitis B surface antigen combined with hepatitis B e antigen as sustained virological response predictors during extended therapy with Peginterferon alfa-2a for hepatitis B e antigen-positive chronic hepatitis B
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- 作者：Jie Chena ; 1 ; Dong-Hua Zhanga ; 1 ; Cheng-Run Xuc ; 1 ; Ming-Yu Zhua ; Zhi-Tao Yanga ; Qi-Ming Gonga ; De-Min Yua ; yby89@163.com" class="auth_mail" title="E-mail the corresponding author ; Xin-Xin Zhanga ; b ; zhangx@shsmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：HBsAg ; hepatitis B surface antigen ; HBeAg ; hepatitis B e antigen ; HBV DNA ; hepatitis B virus DNA ; SVR ; sustained virological response ; NAs ; nucleo(s)tide analogues ; AUC ; area under curve ; CHB ; chronic hepatitis B ; ALT ; alanine aminotransferase ; ORs ; odds ratios ; CIs ; confidence intervals ; ROC ; receiver operating characteristics ; PPV ; positive predictive value ; NPV ; negative predictive value
- 刊名：Journal of Clinical Virology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：72
- 期：Complete
- 页码：88-94
- 全文大小：1097 K
文摘
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We evaluate the promising strategy for chronic hepatitis B patients.
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Extended Peginterferon alfa-2a therapy would benefit chronic hepatitis B patients.
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Quantitative HBsAg combined with HBeAg may predict sustained virological response.