MiR-133a regarded as a potential biomarker for benzene toxicity through targeting Caspase-9 to inhibit apoptosis induced by benzene metabolite (1,4-Benzoquinone)
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- 作者：Yujiao Chen ; Pengling Sun ; Wenlin Bai ; Ai Gao ; gaoai0980@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Benzene ; Biomarker ; miR-133a ; Caspase-9 ; Apoptosis
- 刊名：Science of the Total Environment
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：571
- 期：Complete
- 页码：883-891
- 全文大小：1761 K
文摘
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MiR-133a was involved in benzene-induced hematotoxicity.
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MiR-133a mediated hematotoxicity via regulating 1,4-Benzoquinone-induced apoptosis.
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MiR-133a inhibited 1,4-Benzoquinone–induced abnormal apoptosis through targeting Caspase-9.