Single cell migration dynamics mediated by geometric confinement
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- 作者：Hua Zhanga ; Ruixia Houa ; Peng Xiaoa ; Rubo Xingb ; Tao Chena ; Yanchun Hanb ; Penggang Renc ; Jun Fua ; fujun@nimte.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Graphene oxide micropatterns ; Osteoblasts ; Cell migration ; Cytoskeleton contractility
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：145
- 期：Complete
- 页码：72-78
- 全文大小：2059 K
文摘
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Graphene oxide microstrips are prepared on cell non-adhesive PEG substrates.
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The GO microstrips confine the cell adhesion and migration.
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Dynamic migration of osteoblasts indicate strong adhesive interactions with GO film.
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GO microstrips promote the cytoskeleton contractility to accelerate oriented cell migration.