Expression of stem cell pluripotency factors during regeneration in the earthworm Eisenia foetida
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- 作者：Pengfei Zhenga ; Qiang Shaob ; Xiaoping Diaoa ; ; Zandong Lib ; ; Qian Hana
- 关键词：RACE ; rapid amplification of cDNA ends ; PCR ; polymerase chain reaction ; NCBI ; National Center of Biotechnology Information ; ORF ; open reading frame ; pI ; isoelectric point ; MW ; molecular weight ; BLAST ; Basic Local Alignment Search Tool ; NJ ; neighborjoining ; qRT-PCR ; quantitative polymerase chain reaction ; UTR ; untranslated region ; min ; minutes(s) ; s ; second(s) ; h ; hour(s) ; d ; day ; ES ; embryonic stem cell ; oct4 ; octamer-binding transcription factor 4 ; sox2 ; sex determining region Y box 2 ; klf4 ; kr
- 刊名：Gene
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：575
- 期：1
- 页码：58-65
- 全文大小：1304 K
文摘
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Eisenia foetida full-length sox2 gene and partial oct4, nanog, c-myc and lin28 genes were cloned.
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Expressions of all five cloned genes were up-regulated and tissue specific during regeneration.
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Regeneration of earthworm may involve a process of dedifferentiation and reprogramming.