Changes in ocular biometry and anterior chamber parameters after pharmacologic mydriasis and peripheral iridotomy in primary angle closure suspects

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• 作者：Mohammad Reza Razeghinejad^a ; ^b ; Hamid Lashkarizadeh^a ; Mohammad Hossein Nowroozzadeh^a ; ^{norozzadeh@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Mohammad Yazdanmehr^a
• 关键词：Anterior chamber volume ; Peripheral iridotomy ; Mydriasis ; Narrow angle ; Ocular biometry
• 刊名：Journal of Optometry
• 出版年：2016
• 出版时间：July-September 2016
• 年：2016
• 卷：9
• 期：3
• 页码：189-195
• 全文大小：777 K

文摘

The aim of this study was to evaluate the effects of pharmacologic mydriasis and Peripheral Iridotomy (PI) on ocular biometry and anterior chamber parameters in primary angle closure suspects.

Methods

In this prospective interventional case series, 21 primary angle closure suspects were enrolled. Intraocular pressure, refraction, ocular biometry (Lenstar, LS900), and anterior chamber parameters (Pentacam HR) were measured at four occasions: before PI (before and after mydriasis with phenylephrine) and two weeks after PI (before and after mydriasis). The study was conducted on both eyes and only one eye per patient, in random, was included in the analysis.

Results

The mean age of the participants was 60 ± 7 years and 17 (81%) were female. There were no significant differences in intraocular pressure, refraction, keratometry, biometric and anterior chamber parameters between groups, except for anterior chamber volume, which showed increments with PI and mydriasis. The corresponding values for anterior chamber volume were as follows: 88.2 ± 13.7 mm³ before PI, undilated; 106.3 ± 18.8 before PI, dilated; 99.0 ± 14.6 after PI, undilated, and 107.4 ± 16.5 after PI, dilated (P < 0.001).

Conclusions

This study showed no change in the ocular biometric and anterior chamber parameters including iridocorneal angle after PI and/or pharmacologic mydriasis except for increments in anterior chamber volume. This factor has the potential to be used as a numerical proxy for iris position in evaluating and monitoring patients with primary angle closure suspects after PI.