Eye Hospital of Wenzhou Medical University, Zhejiang, China.
Prospective randomized comparative case series.
Three consecutive scans of the right eye of each subject were obtained using each device in a random order. The following common parameters were recorded: central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, and keratometry (K) readings (steep, flat, and mean). Bland-Altman limits of agreement (LoA) were calculated for the common device parameters.
The study comprised 121 healthy subjects (57 men, 64 women) with a mean age of 25.41 years ± 6.86 (SD) (range 18 to 54 years). The mean difference in CCT was 1.61 μm with LoA of −6.29 to 9.52 μm. The mean difference in the aqueous depth and ACD was 0.02 mm with LoA of −0.10 to 0.14 mm and −0.09 to 0.14 mm, respectively. For the 2.4 mm K readings from the new biometer versus the standard K readings from the Scheimpflug tomographer, the mean difference for flat K, steep K, and mean K was 0.10 diopter (D), 0.05 D, and 0.08 D, respectively. The LoA were −0.17 to 0.38 D, −0.29 to 0.39 D, and −0.19 to 0.34 D, respectively. The CCT, ACD, and all K readings were assessed to be clinically interchangeable.
There was good agreement between the 2 devices for CCT, ACD, aqueous depth, and K readings.
None of the authors has a financial or proprietary interest in any material or method mentioned.