Peptidoglycan recognition protein-S5 functions as a negative regulator of the antimicrobial peptide pathway in the silkworm, Bombyx mori
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- 作者：Kangkang Chen ; Lin Zhou ; Feng Chen ; Yachun Peng ; Zhiqiang Lu ; zhiqiang.lu@nwsuaf.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bombyx mori ; Immune ; Peptidoglycan recognition proteins ; Prophenoloxidase ; Antimicrobial peptide
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：61
- 期：Complete
- 页码：126-135
- 全文大小：2510 K
文摘
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Amidase activity of PGRP-S5 is necessary for activation of the proPO pathway.
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PGRP-S5 negatively regulates antimicrobial peptide generation in silkworms.
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PGRP-S5 acts as a sensor, modulator, and effector in silkworm humoral immunity.