Exposure to perfluoroalkyl substances and thyroid function in pregnant women and children: A systematic review of epidemiologic studies

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• 作者：Virginia Ballesteros^a ; ^b ; Olga Costa^b ; Carmen Iñ ; iguez^b ; ^c ; Tony Fletcher^d ; Ferran Ballester^b ; ^c ; Maria-Jose Lopez-Espinosa^b ; ^c ; ^{lopez_josesp@gva.es}
• 关键词：Prenatal and infant exposure ; Perfluorohexane sulfonate (PFHxS) ; Perfluorooctane sulfonate (PFOS) ; Perfluorooctanoic acid (PFOA) ; Perfluorononanoic acid (PFNA) ; Thyroid
• 刊名：Environment International
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：99
• 期：Complete
• 页码：15-28
• 全文大小：656 K
• 卷排序：99

文摘

First review on PFAS exposure and thyroid outcomes during pregnancy and childhood Scarce comparable studies due to great heterogeneity across them Some evidence of a positive association between maternal PFHxS and PFOS exposure and TSH levels Some evidence of a positive association between TSH and PFNA levels in boys ≥ 11 years No evidence of other thyroid dysfunction or hormones related to PFAS