Isolated rapid eye movement sleep without atonia in amyotrophic lateral sclerosis

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• 作者：Monica Puligheddu^a ; ^b ; ^{puligheddu@unica.it} ; Patrizia Congiu^a ; Debora Aricò ; ^c ; Francesco Rundo^c ; Giuseppe Borghero^b ; Francesco Marrosu^a ; ^b ; Maria Livia Fantini^d ; Raffaele Ferri^c
• 关键词：Amyotrophic lateral sclerosis ; Sleep ; Periodic leg movements during sleep ; Periodicity index ; REM sleep without atonia ; Atonia index
• 刊名：Sleep Medicine
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：26
• 期：Complete
• 页码：16-22
• 全文大小：840 K
• 卷排序：26

文摘

Only few cases with REM sleep behavior disorder (RBD) have been previously reported in amyotrophic lateral sclerosis (ALS). It is unknown if ALS per se impairs sleep motor function, besides respiration. Rapid eye movement (REM) sleep without atonia (RSWA) was found to be frequent in ALS patients without RBD. RSWA without RBD correlates with ALS severity. The mechanisms by which ALS pathology causes RSWA may be multiple and complex.