Aberrant demethylation and expression of MAGEB2 in a subset of malignant peripheral nerve sheath tumors from neurofibromatosis type 1
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- 作者：Yoshimasa Nobeyama ; nobederm@jikei.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hidemi Nakagawa
- 关键词：DNA methylation ; DNA demethylation ; MAGEB2 ; Neurofibromatosis type 1 ; Malignant peripheral nerve sheath tumor
- 刊名：Journal of Dermatological Science
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：81
- 期：2
- 页码：118-123
- 全文大小：953 K
文摘
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MAGEB2 was analyzed for tumors from neurofibromatosis type 1 patients.
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MAGEB2 is methylated in normal Schwann cells and any types of neurofibroma.
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MAGEB2 can be aberrantly demethylated in malignant peripheral nerve sheath tumors.
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MAGEB2 can be aberrantly expressed in malignant peripheral nerve sheath tumors.