Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses
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- 作者：A.H. Klein&dagger ; ; C.L. Joe ; A. Davoodi ; K. Takechi&Dagger ; ; M.I. Carstens ; E. Carstens ; eecarstens@ucdavis.edu" class="auth_mail
- 关键词：AITC ; allyl isothiocyanate ; ANOVA ; analysis of variance ; CA ; cinnamaldehyde ; Cap ; capsaicin ; FPP ; farnesyl phosphopyruvate ; PSTH ; peristimulus time histograms ; SEM ; standard error of the mean ; TRPA ; transient receptor potential ankyrin ; TRPV ; transient receptor potential vanilloid ; Vc ; trigeminal subnucleus caudalis
- 刊名：Neuroscience
- 出版年：20 June 2014
- 年：2014
- 卷：271
- 期：Complete
- 页码：45-55
- 全文大小：1215 K
文摘
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Eugenol and carvacrol activated 7–30% of trigeminal and dorsal root ganglion cells.
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Eugenol and carvacrol enhanced sensory neuronal responses to warmth and noxious heat.
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Eugenol and carvacrol excited heat-sensitive trigeminal caudalis (Vc) neurons.
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Eugenol and carvacrol enhanced Vc neuronal responses to noxious heat.
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Eugenol and carvacrol acted peripherally to enhance lingual warmth and heat sensitivity.