Maternal vitamin D biomarkers are associated with maternal and fetal bone turnover among pregnant women consuming controlled amounts of vitamin D, calcium, and phosphorus

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• 作者：Heyjun Park ; Patsy M. Brannon ; Allyson A. West ; Jian Yan ; Xinyin Jiang ; Cydne A. Perry ; Olga Malysheva ; Saurabh Mehta ; Marie A. Caudill ; ^{mac379@cornell.edu}
• 关键词：ALP ; alkaline phosphatase ; CTx ; carboxy-terminal cross-linking telopeptide of type 1 collagen ; CYP2R1 ; 25-hydroxylase gene ; CYP24A1 ; 24-hydoxylase ; DBP ; vitamin D binding protein ; DPD ; deoxypyridinoline ; GC ; vitamin D binding protein gene ; iPTH ; intact parathyroid hormone ; LMM ; linear mixed model ; NTx ; amino-terminal cross-linking telopeptide of type 1 collagen ; OC ; osteocalcin ; 1 ; 25(OH)2D ; 1 ; 25-dihydroxyvitamin D ; 24 ; 25(OH)2D ; 24 ; 25-dihydroxyvitamin D ; 25(OH)D ; 25-hydroxyvitamin D ; 3-epi-25(OH)
• 刊名：Bone
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：95
• 期：Complete
• 页码：183-191
• 全文大小：479 K
• 卷排序：95

文摘

Pregnancy induces a negative bone balance under adequate nutrient intakes. Higher vitamin D associates with lower maternal bone resorption during pregnancy. This reduction in maternal bone resorption does not influence fetal calcium supply. Higher vitamin D biomarkers may have benefits for bone health of pregnant women.