Pervaporation aided enzymatic production of glycerol monostearate in organic solvents

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• 作者：Z. Ziobrowski ; K. Kiss ; A. Rotkegel ; N. Nemestó ; thy ; R. Krupiczka ; L. Gubicza
• 关键词：Pervaporation ; Glycerol monostearate ; Esterification ; Modeling ; Organic solvent
• 刊名：Desalination
• 出版年：2009
• 出版时间：31 May 2009
• 年：2009
• 卷：241
• 期：1-3
• 页码：212-217
• 全文大小：347 K

文摘

In this paper the enzymatic manufacture of glycerol monostearate was studied in high polar organic solvents. Water produced during the reaction has a disadvantageous effect on the reaction rate and enzyme activity. This byproduct water was removed and the water content was kept constant using a pervaporation unit which could be integrated on-line with the reaction system. The best yield (90 % ) after 6 h reaction time was achieved at 40°C, at seven-fold glycerol excess using dioxane as solvent. The enzymatic esterification reaction could be described by the Random Bi–Bi mechanism. A mathematical model have been estimated and experimentally verified by a set of experiments with varying and constant water contents. The experiments both in batch and integrated system (esterification–pervaporation) could be described with good accuracy by the proposed model.