Safety and efficacy of single-agent bevacizumab-containing therapy in elderly patients with platinum-resistant recurrent ovarian cancer: Subgroup analysis of the randomised phase III AURELIA trial
The PFS and response rate benefit from bevacizumab were similar regardless of age. GradexA0;≥ 3 hypertension was more common with bevacizumab in older vs younger patients. Thromboembolic events were not increased with bevacizumab in patients ≥ 65 vs < 65 years. In older patients, no PRO benefit was seen with bevacizumab versus chemotherapy alone.