To PFKFB3 or Not to PFKFB3, That Is the Question

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• 作者：Cristina Branco¹ ; Randall S. Johnson¹ ; ² ; ^{rsj33@cam.ac.uk}
• 刊名：Cancer Cell
• 出版年：2016
• 出版时间：12 December 2016
• 年：2016
• 卷：30
• 期：6
• 页码：831
• 全文大小：109 K
• 卷排序：30

文摘

In this issue of Cancer Cell, Cantelmo et al. describe how reduction of PFKFB3 enzyme activity can promote vascular normalization. The authors show in turn how this affects vascular permeability and can ultimately improve the efficacy of chemotherapeutic agents.