Multi-generational xenoestrogenic effects of Perfluoroalkyl acids (PFAAs) mixture on Oryzias latipes using a flow-through exposure system

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• 作者：Jin Wuk Lee^a ; Jae-Woo Lee^a ; Yu-Jin Shin^a ; Ji-Eun Kim^a ; Tae-Kwon Ryu^b ; Jisung Ryu^b ; Jaean Lee^c ; Pilje Kim^a ; Kyunghee Choi^d ; Kyunghwa Park^a ; ^{mirrorpark@korea.kr}
• 关键词：Perfluorooctane sulfonate (PFOS) ; Perfluroroctanoic acid (PFOA) ; Perfluorobutane sulfonate (PFBS) ; Perfluorononanoic acid (PFNA) ; Oryzias latipes ; Multi-generational estrogenic effects
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：169
• 期：Complete
• 页码：212-223
• 全文大小：2841 K
• 卷排序：169

文摘

In all PFAAs, PFOS showed the highest cumulative potential in Oryzias latipes. PFAAs caused significant increase of vitellogenin expression only in last generation, F2. Fecundity was suppressed by PFAAs exposure as generation goes from F0 to F2. PFAAs caused sex ratio disturbance relative to control.