Secretory function of ovarian cells and myometrial contractions in cow are affected by chlorinated insecticides (chlordane, heptachlor, mirex) in vitro
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- 作者：Michael Hubert Wrobel ; m.wrobel@pan.olsztyn.pl ; Jaroslaw Mlynarczuk
- 关键词：AA ; arachidonic acid ; Act D ; actinomycin D ; DDE ; dichlorodiphenyldichloroethylene ; DDT ; dichlorodiphenyltrichloroethane ; E2 ; estradiol ; KRS ; Krebs-Ringer's solution ; MTT ; tetrazolium salt ; NP-I/OT ; neurophysin-I/OT ; OT ; oxytocin ; P4 ; progesterone ; PCBs ; polychlorinated biphenyls ; PGA ; peptidyl-glycine-α-amidating monooxygenase ; PG(s) ; prostaglandin(s) ; PGFM ; 13 ; 14-dihydro-15-keto-PGF2α ; T ; testosterone ; TBP ; TATA box binding protein
- 刊名：Toxicology and Applied Pharmacology
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：314
- 期：Complete
- 页码：63-71
- 全文大小：973 K
- 卷排序：314
文摘
The studied insecticides affected steroids and oxytocin secretion from ovaries. Mirex stimulated bovine myometrial contractions. Heptachlor inhibited bovine myometrial contractions. Prostaglandins are not involved in adverse effect of the insecticides on uterine contractions.