Discovery of indole-based tetraarylimidazoles as potent inhibitors of urease with low antilipoxygenase activity
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- 作者：Sadia Naureena ; phdline123@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Faryal Chaudhrya ; Nadia Asifa ; Munawar Ali Munawara ; Muhammad Ashrafb ; Faizul Hassan Nasimb ; Humera Arshadb ; Misbahul Ain Khana ; b
- 关键词：Multicomponent reaction ; Thiourea ; Ammonium acetate ; Urease inhibition ; Lipoxygenase inhibition
- 刊名：European Journal of Medicinal Chemistry
- 出版年：2015
- 出版时间：18 September 2015
- 年：2015
- 卷：102
- 期：Complete
- 页码：464-470
- 全文大小：733 K
文摘
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Synthesis of a series of novel indole based tetraarylimidazoles.
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A new class of potent inhibitors of urease enzyme.
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Lower inhibition profiles for lipooxygenase.