Benzimidazole resistance survey for Haemonchus, Teladorsagia and Trichostrongylus in three European countries using pyrosequencing including the development of new assays for Trichostrongylus

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• 作者：Sabrina Ramü ; nke^a ; ¹ ; Lynsey Melville^b ; ¹ ; Laura Rinaldi^c ; Hubertus Hertzberg^d ; Theo de Waal^e ; Georg von Samson-Himmelstjerna^a ; Giuseppe Cringoli^c ; Fabien Mavrot^d ; Philip Skuce^b ; Jü ; rgen Krü ; cken^a ; Janina Demeler^a ; ^{J.demeler@fu-berlin.de}
• 关键词：Trichostrongylus colubriformis ; Nematode ; Diagnosis ; Benzimidazole ; Resistance ; Single nucleotide polymorphism ; Sheep ; Europe
• 刊名：International Journal for Parasitology: Drugs and Drug Resistance
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：6
• 期：3
• 页码：230-240
• 全文大小：1176 K
• 卷排序：6

文摘

Successful development of a pyrosequencing assay for Trichostrongylus. Resistance survey revealed high number of SNPs present in all three countries. SNP at codon 200 most prevalent in European trichostrongyloid populations. Low number of SNPs found in Italy corresponds to FECRT data. Pyrosequencing successfully employed as a tool for large scale surveys.