The C1B domains of novel PKC蔚 and PKC畏 have a higher membrane binding affinity than those of the also novel PKC未 and PKC胃
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- 作者：Antonio L. Egea-Jimé ; nez ; Senena Corbalá ; n-Garcí ; a ; Juan C. Gó ; mez-Ferná ; ndez ; jcgomez@um.es" class="auth_mail
- 关键词：OG-PE ; N-(5-dimethylaminonaphthalene-1-sulfonyl)-1 ; 2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine ; DOG ; 1 ; 2-sn-dioleoylglycerol ; ECFP ; enhanced cyan fluorescent protein ; SAG ; 1-stearoyl-oleoyl-sn-glycerol ; DPG ; 1 ; 2-sn-dipalmitoylglycerol ; DOcPA ; 1 ; 2-dioctanoyl-sn-phosphatidic acid ; POPG ; 1-palmitoyl-2-oleoyl-sn phosphatidylglycerol ; POPA ; 1-palmitoyl-2-oleoyl-sn-phosphatidic acid ; POPC ; 1-palmitoyl-2-oleoyl-sn-phosphatidylcholine ; POPS ; 1-palmitoyl-2-oleoyl-sn-phoshatidylserine ; DOcG ; 1 ; 2-dio
- 刊名：Biochimica et Biophysica Acta (BBA)/Biomembranes
- 出版年：July 2014
- 年：2014
- 卷：1838
- 期：7
- 页码：1898-1909
- 全文大小：1368 K
文摘
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C1B蔚 and C1B畏 bind to negatively charged phospholipid vesicles more strongly than C1B未 and C1B胃.
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These two groups of C1B domains were distinguished both in the presence and in the absence of diacylglycerol.
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These binding differences were also observed in RBL-2H3 cells.