Phosphorus nitrogen compounds: Part 34. Syntheses, structural investigations, cytotoxic and biological activities of spiro-ansa-spiro and spiro-bino-spiro tetrameric phosphazene derivatives
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- 作者：İpek Berberoğlua ; Nuran Asmafiliza ; Zeynel Kılıç ; a ; zkilic@science.ankara.edu.tr" class="auth_mail" title="E-mail the corresponding author ; Tuncer Hö ; kelekb ; L. Yasemin Koç ; c ; Leyla Aç ; ıkd ; Mustafa Tü ; rke ; Hossien Soltanzaded ; Hakan Dalf
- 关键词：Cyclotetraphosphazenes ; Syntheses ; Spectroscopy ; Crystal structure ; Cytotoxicity ; Biological activity
- 刊名：Inorganica Chimica Acta
- 出版年：2016
- 出版时间：1 May 2016
- 年：2016
- 卷：446
- 期：Complete
- 页码：75-86
- 全文大小：1313 K
文摘
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The new spiro-ansa-spiro and spiro-bino-spiro cyclotetraphosphazenes were prepared.
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The structures of these compounds were made.
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The new phosphazenes were screened for antimicrobial activity.
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The compounds were tested against L929 Fibroblast and MDA-MB 231 breast cancer cells.
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The interactions between all the compounds and pBR322 plasmid DNA were examined.