The preparation and applications of novel phosphazene crosslinked thermo and pH responsive hydrogels

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• 作者：Hava Ozay^a ; Ozdem Sahin^a ; Omer Kaan Koc^a ; Ozgur Ozay^b ; ^{ozgurozay@comu.edu.tr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Hydrogel ; Phosphazene ; Thermo responsive ; Catalyst ; Drug release
• 刊名：Journal of Industrial and Engineering Chemistry
• 出版年：2016
• 出版时间：25 November 2016
• 年：2016
• 卷：43
• 期：Complete
• 页码：28-35
• 全文大小：1696 K

文摘

In this study, we synthesized a novel phosphazene compound hexakis[4-(acrylamido)phenoxy]cyclotriphosphazene (HAAP) as crosslinker. The structure of compound was identified using spectroscopic techniques. Then, HAAP was used as crosslinker for the synthesis of thermo and pH responsive p(NIPAM-co-VI) hydrogels. The structure and swelling behavior of hydrogel was investigated. Then, HAAP-crosslinked p(NIPAM-co-VI) hydrogels were used for in vitro release of Rhodamine 6G as drug release matrix. Additionally, HAAP-crosslinked p(NIPAM-co-VI) hydrogels were used as support material for the preparation of cobalt metal catalysts. The prepared HAAP-crosslinked p(NIPAM-co-VI)-Co composite catalyst was used as catalyst for the reduction reaction of 4-nitrophenol.