刊名:Biochimica et Biophysica Acta (BBA) - Biomembranes
出版年:2017
出版时间:February 2017
年:2017
卷:1859
期:2
页码:146-154
全文大小:789 K
卷排序:1859
文摘
The uncoupled nAChR does not undergo agonist-induced conformational transitions. The agonist site exhibits resting state-like agonist binding affinity. The transmembrane pore does not bind typical fluorescent channel blockers. A distinct conformation of the uncoupled pore may be similar to that of ELIC.