Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures

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• 作者：Dorota G. Piotrowska^a ; ^{dorota.piotrowska@umed.lodz.pl} ; Graciela Andrei^b ; Dominique Schols^b ; Robert Snoeck^b ; Magdalena Łysakowska^a
• 关键词：Phosphonates ; Isoxazolidines ; Quinazoline-2 ; 4-diones ; Antiviral ; Cytostatic
• 刊名：European Journal of Medicinal Chemistry
• 出版年：2017
• 出版时间：27 January 2017
• 年：2017
• 卷：126
• 期：Complete
• 页码：84-100
• 全文大小：663 K
• 卷排序：126

文摘

1,3-Disubstituted quinazoline-2,4-diones containing isoxazolidine-3-yl-3-phosphonate moiety. Anti-varicella-zoster virus active substituted quinazoline-2,4-diones. Anti-cytomegalovirus active substituted quinazoline-2,4-diones. Cytostatic potency of substituted quinazoline-2,4-diones.