Phosphorylation of proteins during human myometrial contractions: A phosphoproteomic approach

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• 作者：Claire A. Hudson^a ; ^{Claire.hudson@bristol.ac.uk} ; André ; s Ló ; pez Bernal^a ; ^b ; ^{A.LopezBernal@bristol.ac.uk}
• 关键词：Myosin light chain kinase ; Parturition ; Phosphoproteomics ; Myometrium ; Uterus ; Contractility
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：22 January 2017
• 年：2017
• 卷：482
• 期：4
• 页码：1393-1399
• 全文大小：962 K
• 卷排序：482

文摘

First quantitative mass spectrometry analysis of the myometrial phosphoproteome. 22 phosphopeptides change during spontaneous or oxytocin-driven phasic contractions. MYLK phosphorylation on serine 1760 is highly coupled to myometrial force.