Aging effects on oxidative phosphorylation in rat adrenocortical mitochondria
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- 作者：Paola Solinasa ; 1 ; Hisashi Fujiokab ; Tomas Radivoyevitchc ; Bernard Tandlerd ; Charles L. Hoppela ; charles.hoppel@case.edu" class="auth_mail
- 关键词：Mitochondria ; Adrenal cortex ; Oxidative phosphorylation ; Aging ; Fischer 344 rat
- 刊名：Mechanisms of Ageing and Development
- 出版年：June 2014
- 年：2014
- 卷：138
- 期：Complete
- 页码：10-14
- 全文大小：871 K
文摘
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We assessed adrenal cortex mitochondrial oxidative phosphorylation.
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Young and elderly rats from 3 strains were studied.
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Mitochondrial yields were similar in all rat strains irrespective of age.
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Aging does not affect mitochondrial activity, except in the Fischer 344 rat.
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Maximal ADP-stimulated oxidative phosphorylation decreased with age in F344 rats.