FT-IR characterization of a theranostic nanoprobe for photodynamic therapy and epidermal growth factor receptor targets

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• 作者：M.L. Castilho^aAuthor Vitae ; K.C. Hewitt^bAuthor Vitae ; L. Raniero^a ; ^{lraniero@univap.br} ; ^{lraniero@gmail.com}Author Vitae
• 关键词：Photodynamic therapy ; FT-IR ; Gold nanoparticle ; Epidermal growth factor ; Chlorin e6
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：240
• 期：Complete
• 页码：903-908
• 全文大小：1396 K
• 卷排序：240

文摘

Develop a bifunctional theranostic nanoprobe for breast cancer treatment. Epidermal Growth Factor is a targeting agent. The Chlorin e6 attached to nanoparticle carrier increases the pharmacokinetics. Diagnostic and therapeutic complexes formation were characterized by FT-IR. Promising nanoprobe for photodynamic therapy for cells with EGFR overexpressed.