SiO2/PEG quercetin organic-inorganic hybrids were synthesized via sol-gel.
The formation of apatite on materials surface after SBF proved their bioactivity.
Viability of NIH-3T3 cells was significantly increased by exposure to the hybrids.
Viability of PC-12 and U-251 cell lines was not affected by new materials.
SH-SY5Y cell proliferation was inhibited and their morphology was changed by hybrids.