Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue
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- 作者：Collingridge ; David R. ; Piepmeier ; Joseph M. ; Rockwell ; Sara ; Knisely ; Jonathan P.S.
- 关键词：Tumour oxygenation ; Brain tumours ; Glioma ; Peritumoural tissue
- 刊名：Radiotherapy and Oncology
- 出版年：1999
- 出版时间：November 1, 1999
- 年：1999
- 卷：53
- 期：2
- 页码：127-131
- 全文大小：140 K
文摘
This study quantifies the spatial distribution of pO2 in glioma and in the surrounding brain tissue. Both glioma and peritumoural brain contain regions at oxygen tensions less than 2.5 mmHg. Modalities targeting hypoxia to improve the efficacy of therapy may have an important role in the management of this disease.