Efficacy of moxidectin injectable and pour-on formulations in a pilot control program against bovine hypodermosis in Southern Italy

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• 作者：Otranto ; Domenico ; Lia ; Riccardo P. ; Agostini ; Alessandro ; Traversa ; Donato ; Milillo ; Piermarino ; et. al.
• 关键词：Hypoderma ; Italy ; Control program ; Moxidectin
• 刊名：Preventive Veterinary Medicine
• 出版年：2005
• 出版时间：June 10, 2005
• 年：2005
• 卷：69
• 期：1-2
• 页码：153-159
• 全文大小：89.0 K

文摘

Bovine hypodermosis is a myiasis caused by Hypoderma bovis and Hypoderma lineatum (Diptera, Oestridae) larvae, which has a severe economic impact on the livestock industry. Though myiasis is widespread throughout Italy, no nationwide eradication program has ever been planned, unlike in other European Countries. With a view to setting up a national control program, a pilot study was carried out in Southern Italy on 9939 cattle bred in an area with a high prevalence of cattle hypodermosis, using moxidectin 0.5 % pour-on (Cydectin^®, Fort Dodge) and 1 % injectable (Cydectin^®, Fort Dodge) formulations. At the recommended dosage, moxidectin displayed efficacy levels of 99.9 % in the pour-on and 100 % in the injectable formulation, whereas the microdose (1 mg per head regardless of body weight) was less effective (65.7 % ). This trial contributed to a significant reduction in infestation rates in the study area and represented the first step through which a national program for eradicating warble fly infestation in Italy.