Hierarchical identification of bioactive components in a medicinal herb by preparative high-performance liquid chromatography and selective knock-out strategy

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• 作者：Cheng Qu^a ; ¹ ; Lin-Yan Wang^a ; ¹ ; Hang Lin^a ; Er-Xin Shang^a ; Yu-Ping Tang^a ; ^{yupingtang@njucm.edu.cn} ; Shi-Jun Yue^a ; Yi Jin^a ; Wei-Wei Tao^a ; Shao-Ping Li^b ; Yong-Qing Hua^a ; Pei Liu^a ; Shu-Lan Su^a ; Huiping Zhou^c ; Da-Wei Qian^a ; Jin-Ao Duan^a
• 关键词：Safflower ; Herb ; Contribution ; Component ; High-performance liquid chromatography ; Knock-out
• 刊名：Journal of Pharmaceutical and Biomedical Analysis
• 出版年：2017
• 出版时间：20 February 2017
• 年：2017
• 卷：135
• 期：Complete
• 页码：206-216
• 全文大小：3137 K
• 卷排序：135

文摘

An approach was established for differentiating effect contribution of herbal components. Knock-out of herbal components was accomplished by using prep-HPLC. A heat map and a 3D score plot were used. This approach was successfully applied for investigating the safflower.