Rumphellclovane A, a novel clovane-related sesquiterpenoid from the gorgonian coral Rumphella antipathies

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• 作者：Hsu-Ming Chung ; Yung-Husan Chen ; Tsong-Long Hwang ; Li-Fan Chuang ; Wei-Hsien Wang ; Ping-Jyun Sung
• 关键词：Rumphella antipathies ; Rumphellclovane ; Clovane ; Sesquiterpenoid
• 刊名：Tetrahedron Letters
• 出版年：2010
• 出版时间：19 May 2010
• 年：2010
• 卷：51
• 期：20
• 页码：2734-2736
• 全文大小：219 K

文摘

A novel clovane-related derivative, rumphellclovane A (1), which was found to possess a new carbon skeleton, and a new natural clovane, 2β-hydroxyclovan-9-one (2), were isolated from the gorgonian coral Rumphella antipathies. The structures of metabolites 1 and 2 were elucidated by spectroscopic analysis and by comparison of the spectral data with those of related clovane analogues. A plausible biosynthetic pathway of 1 was proposed.