Differential roles of PKC isoforms (PKCs) and Ca2+ in GnRH and phorbol 12-myristate 13-acetate (PMA) stimulation of p38MAPK phosphorylation in immortalized gonadotrope cells
GnRH and PMA stimulate p38MAPK phosphorylation in αT3-1 and LβT2 gonadotrope cells. Selective PKCs play a role in p38MAPK phosphorylation in a ligand-and cell context-dependent manner. Different Ca2 pools play a role in p38MAPK phosphorylation in αT3-1 vs. LβT2 cells.