Layer II of placental syncytiotrophoblasts expresses MDR1 and BCRP at the apical membrane in rodents
详细信息 查看全文
- 作者：Tomoya Akashia ; Tomohiro Nishimuraa ; Yoshiya Takakia ; Masaya Takahashia ; Bo-Chul Shinb ; Masatoshi Tomia ; tomi-ms@pha.keio.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Emi Nakashimaa
- 关键词：SynTI ; syncytiotrophoblast layer I ; SynT-II ; syncytiotrophoblast layer II ; MDR1 ; multidrug resistance protein 1 ; BCRP ; breast cancer resistance protein ; GLUT1 ; glucose transporter 1 ; Cx26 ; connexin 26
- 刊名：Reproductive Toxicology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：65
- 期：Complete
- 页码：375-381
- 全文大小：3759 K
文摘
- •
In rodents, MDR1 and BCRP are expressed in syncytiotrophoblast layer II.
- •
In layer II, MDR1 and BCRP are localized in the apical membrane.
- •
Layer II plays a defensive role in the machinery of the placental barrier.