Serum ethanolamine plasmalogens improve detection of cognitive impairment among elderly with high excretion levels of urinary myo-inositol: A cross-sectional study
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- 作者：Ryouta Maebaa ; maeba@med.teikyo-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Atsushi Arakib ; Kenji Ishiic ; Kishiko Ogawad ; Yoshiaki Tamurab ; Masashi Yasunagad ; Ushio Minamid ; Aya Komoria ; Tomoki Okazakia ; Megumi Nishimukaie ; Hiroshi Haraf ; Yoshinori Fujiwarad
- 关键词：Aβ1-40 ; amyloid β 1&ndash ; 40 ; AD ; Alzheimer's disease ; CDR ; clinical dementia rating ; CH ; cholesterol ; CI ; cognitive impairment ; CIST ; cognitive impairment screening test ; HbA1c ; hemoglobin A1c ; MCO ; memory clinic outpatient ; MI ; myo-inositol ; MMSE ; Mini-Mental State Examination ; NE ; cognitively normal elderly ; Pls ; plasmalogens ; PlsEtn ; ethanolamine plasmalogen ; T2DM ; type 2 diabetes mellitus ; UMI ; urinary myo-inositol
- 刊名：Clinica Chimica Acta
- 出版年：2016
- 出版时间：30 January 2016
- 年：2016
- 卷：453
- 期：Complete
- 页码：134-140
- 全文大小：662 K
文摘
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Serum ethanolamine plasmalogen was independent factor for cognitive impairment (CI).
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Urinary myo-inositol (UMI) was associated with serum hemoglobin A1c.
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The interaction between serum ethanolamine plasmalogen and UMI for CI was confirmed.
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Combined usage of ethanolamine plasmalogen (PlsEtn) and UMI improved detection of CI.
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Serum PlsEtn may be useful in detecting CI among elderly with hyperglycemia.