• 作者：Mar&#237 ; a del Prado Talavera-Rubio ; ^{mdtalavera@hotmail.com} ; Ana Mar&#237 ; a Garc&#237 ; a-Vicente ; Azahara Mar&#237 ; a Palomar-Muñ ; oz ; John Patrick Pilkington-Woll ; V&#237 ; ctor Manuel Poblete-Garc&#237 ; a ; Á ; ngel Soriano-Castrejó ; n
• 关键词：Tumor de origen desconocido ; Tomografí ; a por emisió ; n de positrones con 18F-fluorodesoxiglucosa ; Tomografí ; a computarizada
• 刊名：Medicina Cl¡§anica
• 出版年：2013
• 出版时间：5 January, 2013
• 年：2013
• 卷：140
• 期：1
• 页码：14-19
• 全文大小：752 K

Background and objective

We determined the utility of the ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography (PET)-computerized tomography (CT) in the localization of the primary tumor in patients with tumor of unknown origin (TUO).

Patients and method

¹⁸F-FDG PET-CT scans, performed between November 2006 and November 2010, in search for the primary tumor in patients with TUO, were retrospectively evaluated. Patients underwent a standard PET-CT, 50-60 minutes after intravenous injection of 296-370 MBq ¹⁸F-FDG. PET-CT studies were assessed as pathological, with/without identification of the primary tumour and no pathological. Final diagnosis was established by histological confirmation and/or clinical/radiologic follow-up longer than 6 months.

Results

We studied 74 patients (59 males, 15 females), with ages ranging from 41-89 years. In 38 (51 % ) patients the PET-CT assessed the correct origin of the primary tumour. In 8 cases, a histological confirmation in the primary lesion was obtained. In 4 patients the PET-CT showed a false positive result.

Conclusion

PET-CT scanning identified 51 % of the primary sites in our sample of patients.