Boron-doped diamond electrochemical sensor for sensitive determination of nicotine in tobacco products and anti-smoking pharmaceuticals
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- 作者：慕ubom铆r 艩vorc ; Dalibor M. Stankovi膰 ; Kurt Kalcher
- 关键词：ACS ; alumina coated silica ; AMP ; amperometry ; AP ; anodically pretreated ; BDDE ; boron-doped diamond electrode ; BPPGE ; basal plane pyrolytic graphite electrode ; BRBS ; Britton&ndash ; Robinson buffer solution ; CNC ; carbon nanotube cluster ; CV ; cyclic voltammetry ; DPP ; differential pulse polarography ; DPV ; differential pulse voltammetry ; Ep ; peak potential ; GCE ; glassy carbon electrode ; LCR ; linear concentration range ; LOD ; detection limit ; MF ; mercury film ; MWCNT ; multi-walled carbon nanotube ; NCB ; n
- 刊名：Diamond and Related Materials
- 出版年：February, 2014
- 年：2014
- 卷：42
- 期：Complete
- 页码：1-7
- 全文大小：630 K
文摘
A sensitive, selective and reliable electrochemical method for the determination of nicotine using differential pulse voltammetry on a bare boron-doped diamond electrode has been developed. Nicotine yielded a single oxidation peak at a highly positive potential of + 1.45 V (vs. Ag/AgCl/3 M KCl) in Britton-Robinson buffer solution at pH 8. The influence of supporting electrolyte, pH and scan rate on the current response of NIC was investigated. At optimized experimental conditions, a linear relation between peak current and concentration of nicotine was found for the range from 0.5 to 200 渭M (0.08-32.9 mg L鈭?#xA0;1) with a detection limit of 0.3 渭M (0.05 mg L鈭?#xA0;1) and a good repeatability (relative standard deviation of 2.1% at 25 渭M concentration level, n = 10) was achieved without any electrode surface modification. The practical usefulness of the developed procedure was successfully demonstrated with the determination of nicotine in tobacco products and anti-smoking pharmaceuticals with results similar to those obtained by a high-performance liquid chromatography and to the contents declared by the manufacturer, respectively. Prior to analysis, the sample pretreatment includes only sonication and/or simple liquid-liquid extraction. The proposed sensor represents an effective electrochemical tool and a promising alternative for quality control analysis of products in tobacco and pharmaceutical industry.