Synthesis of a nitrogen mustard ligand on a cobalt(III) metal centre

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• 作者：Alan M. Downward ; Matthew I.J. Polson ; William R. Kerr ; Janadari Kariyawasam ; Richard M. Hartshorn ; ^{richard.hartshorn@canterbury.ac.nz}
• 关键词：Cobalt ; Mustard ligand ; Diastereoisomers
• 刊名：Polyhedron
• 出版年：2013
• 出版时间：22 March, 2013
• 年：2013
• 卷：52
• 期：Complete
• 页码：617-622
• 全文大小：603 K

文摘

N-(2-hydroxyethyl)ethane-1,2-diamine (heen) can be coordinated to give a single diastereoisomer of (OC-6-12¡ä)-[Co(heen)₂(NO₂)₂](NO₃), one of many possible isomers, which has been crystallographically characterised. The pendant alcohol groups can be then converted to the related alkyl halide. This represents a way of preparing a complex of a mustard ligand without having to prepare or handle the mustard itself.