Highly lipophilic pluronics-conjugated polyamidoamine dendrimer nanocarriers as potential delivery system for hydrophobic drugs
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- 作者：Thi Tram Chau Nguyena ; b ; Cuu Khoa Nguyenc ; nckhoavnn@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Thi Hiep Nguyend ; Ngoc Quyen Trana ; c ; tnquyen@iams.vast.vn" class="auth_mail" title="E-mail the corresponding author ; tnquyen979@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Polyamidoamine dendrimer ; Nanocarrier ; Lipophilic pluronic ; 5-FU ; Delivery
- 刊名：Materials Science & Engineering C
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：70
- 期：part_P2
- 页码：992-999
- 全文大小：2157 K
文摘
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Biocompatible pluronic-conjugated polyamidoamine dendrimers were prepared at nanoscale for drug delivery.
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The dendrimer nanocarrier was decorated with a lipophilic pluronic exhibiting a higher drug loading efficiency.
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The pluronic-functionalized nanocarriers demonstrated a great potential for delivering hydrophobic drugs.