Immunochemical detection of the occupational allergen, methylene diphenyl diisocyanate (MDI), in situ
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- 作者：Adam V. Wisnewski ; adam.wisnewski@yale.edu" class="auth_mail" title="E-mail the corresponding author ; Jian Liu Jian.liu@yale.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Methylene-diphenyl-diisocyanate (MDI) ; Antiserum ; Airways ; Occupational asthma
- 刊名：Journal of Immunological Methods
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：429
- 期：Complete
- 页码：60-65
- 全文大小：1124 K
文摘
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A polyclonal rabbit antiserum was developed against the occupational allergen, methylene diphenyl diisocyanate (MDI).
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MDI-specific polyclonal rabbit IgG recognizes MDI in a hapten-like manner (e.g. conjugated to different carrier proteins).
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MDI-specific rabbit antiserum provides a useful probe for localizing MDI within cells and tissue sections from exposed hosts.