The mining chemical Polydadmac is cytotoxic but does not interfere with Cu-induced toxicity in Atlantic salmon hepatocytes
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- 作者：På ; l A. Olsvika ; pal.olsvik@nifes.no" class="auth_mail" title="E-mail the corresponding author ; Marc H.G. Berntssena ; Rune Waagbø ; a ; Ernst Hevrø ; ya ; b ; Liv Sø ; ftelanda
- 关键词：Mining activity ; Processing chemicals ; Polydadmac ; Environmental pollution ; Fish ; Transcriptional responses
- 刊名：Toxicology in Vitro
- 出版年：2015
- 出版时间：25 December 2015
- 年：2015
- 卷：30
- 期：1
- 页码：492-505
- 全文大小：1813 K
文摘
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We examine cytotoxicity and mechanistic effects of Polydadmac on fish cells.
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Polydadmac but not Dadmac is cytotoxic to Atlantic salmon hepatocytes.
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Synergism was seen between Dadmac and Cu on mnsod.
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Polydadmac does not interfere with Cu toxicity.