Water-soluble inclusion complexes of trans-polydatin by cyclodextrin complexation: Preparation, characterization and bioactivity evaluation
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- 作者：Jian-Qiang Zhanga ; Kun-Ming Jianga ; Xiao-Guang Xiea ; xgxie@ynu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yi Jina ; jinyi@ynu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jun Lina ; b ; linjun@ynu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：trans-Polydatin ; Cyclodextrins ; Characterization ; Inclusion complex ; In vitro activity
- 刊名：Journal of Molecular Liquids
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：219
- 期：Complete
- 页码：592-598
- 全文大小：1131 K
文摘
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The inclusion complexes of PD/CDs were studied by apparatus approaches.
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NMR and ESI-MS provided conclusive evidence for the formation of inclusion complexes.
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The water solubility of PD was significantly increased by complexation with CDs.
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The antitumor activities of PD/CDs were tested and effectively improved over free PD in vitro.