Ponciretin attenuates ethanol-induced gastric damage in mice by inhibiting inflammatory responses

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• 作者：Geum-Dan Kang ; Dong-Hyun Kim ; ^{dhkim@khu.ac.kr}
• 关键词：ELISA ; enzyme-linked immunosorbent assay ; IFN ; interferon ; IL ; interleukin ; LPS ; lipopolysaccharide ; PCR ; polymerase chain reaction ; TNF ; tumor necrosis factor
• 刊名：International Immunopharmacology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：43
• 期：Complete
• 页码：179-186
• 全文大小：1248 K
• 卷排序：43

文摘

Ponciretin and poncirin inhibited IL-8 expression and NF-κB activation in ethanol- or LPS-stimulated KATO III cells Ponciretin and poncirin protected ethanol-induced gastric injury in mice Ponciretin and poncirin inhibited ethanol-induced secretion of CXCL-4 and IFN-γ in mice Ponciretin and poncirin inhibited ethanol-induced NF-κB activation in mice Anti-gastritis effect of ponciretin was greater than that of poncirin in vitro and in vivo.