Identification of hepatitis C virus genotype 3 by a commercial assay challenged by natural polymorphisms detected in Spain from patients with diverse origins
详细信息 查看全文
- 作者：Veró ; nica Saludesa ; b ; Josep Querc ; d ; e ; Josep Gregoric ; d ; f ; Elisabet Bascuñ ; anaa ; Damir Garcí ; a-Cehicc ; d ; Juan Ignacio Estebanc ; d ; e ; Vicente Ausinaa ; e ; g ; Elisa Martró ; a ; b ; emartro.igtp.germanstrias@gencat.cat" class="auth_mail" title="E-mail the corresponding author
- 关键词：HCV ; hepatitis C virus ; HCV-3 ; genotype 3 ; UDPS ; ultradeep pyrosequencing ; 5&prime ; UTR ; 5&prime ; untranslated region
- 刊名：Journal of Clinical Virology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：78
- 期：Complete
- 页码：14-19
- 全文大小：535 K
文摘
- •
We report the largest series of hepatitis C virus (HCV) isolates genotyped by the Abbott assay.
- •
An indeterminate result was obtained in 7.95% of HCV-3 cases at a Spanish center.
- •
These indeterminate results were caused by one to three mismatches in the HCV-3 probe-binding region.
- •
These natural polymorphisms were detected in patients with diverse origins.