Synthesis and characterisation of chitosan-graft

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• 作者：Natasha H. Munro ; Lyall R. Hanton ; Stephen C. Moratti ; Brian H. Robinson
• 关键词：Chitosan ; ATRP ; Graft copolymers
• 刊名：Carbohydrate Polymers
• 出版年：2009
• 出版时间：11 July 2009
• 年：2009
• 卷：77
• 期：3
• 页码：496-505
• 全文大小：570 K

文摘

Two synthetic routes, “grafting-from” and “grafting-to” the chitosan backbone, were investigated to prepare chitosan-graft-poly(OEGMA) copolymers by ATRP. The copolymers were characterised by ¹H NMR and FT-IR spectroscopy, elemental analyses and GPC. Estimates of the degree of grafting were quantitatively found from integration of the ¹H NMR spectra. The GPC data indicated that the hydrodynamic volumes of the polymers were significantly altered by the incorporation of poly(OEGMA). A comparison of the two synthetic methods showed differences in the ratio of synthetic and natural polymers present in the resulting combs. The “grafting-to” synthetic route was preferable as the polymers were of higher purity and more defined.