Polyoxygenated steroids from the gorgonian Menella woodin with capabilities to modulate ROS levels in macrophages at response to LPS
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- 作者：Vu A. Tua ; 1 ; Ekaterina G. Lyakhovab ; 1 ; Chau N. Diepa ; Anatoly I. Kalinovskyb ; Pavel S. Dmitrenokb ; Nguyen X. Cuonga ; Nguyen V. Thanha ; Ekaterina S. Menchinskayab ; Evgeny A. Pislyaginb ; Nguyen H. Nama ; Phan V. Kiema ; Valentin A. Stonikb ; stonik@piboc.dvo.ru" class="auth_mail" title="E-mail the corresponding author ; Chau V. Minha ; cvminh@vast.vn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Polyoxygenated steroids ; Gorgonian coral ; Menella woodin ; NMR ; Macrophages ; ROS
- 刊名：Steroids
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：104
- 期：Complete
- 页码：246-251
- 全文大小：537 K
文摘
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The polyoxygenated sterols of the Vietnamese Menella woodin were investigated.
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Four new polyoxygenated steroids were isolated and structurally elucidated.
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Three isolated steroids have shown a reduction of ROS levels in macrophages.