Structural characterization and biomedical properties of sulfated polysaccharide from the gladius of Sepioteuthis lessoniana (Lesson, 1831)
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- 作者：Palaniappan Seedevi ; seedevisalem@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Meivelu Moovendhan ; Shanmugam Vairamani ; Annian Shanmugam
- 关键词：Bioactivity ; NMR ; FT-IR ; Sulfated polysaccharide ; S. lessoniana
- 刊名：International Journal of Biological Macromolecules
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：85
- 期：Complete
- 页码：117-125
- 全文大小：2957 K
文摘
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The molecular weight of sulfated polysaccharide was found to be as 66 kDa and it composed of rhamnose, galactose, xylose, and glucose.
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The structural features of sulfated polysaccharide were analyzed through FT-IR and NMR spectroscopy.
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The sulfated polysaccharide showed classical antibiotic action at low concentration level against human pathogens.
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The sulfated polysaccharide has showed low toxicity level on Vero cell lines at the same time it has showed good anticancer effect at lower concentration level on HeLa cell lines.