In vitro fermentation of sulfated polysaccharides from E. prolifera and L. japonica by human fecal microbiota

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• 作者：Qing Kong ; ^{kongqing@ouc.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Shiyuan Dong ; Jian Gao ; Chaoyu Jiang
• 关键词：Enteromorpha prolifera ; Laminaria japonica ; In vitro fermentation
• 刊名：International Journal of Biological Macromolecules
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：91
• 期：Complete
• 页码：867-871
• 全文大小：584 K

文摘

In vitro fermentation of the sulfated polysaccharides from seaweeds Enteromorpha prolifera and Laminaria japonica and their prebiotic effects on human fecal microbiota were investigated in this study. The sulfated polysaccharides were fermented in vitro for 48 h by human fecal cultures. When 0.8 g MWCOL (polysaccharides MWCO < 30 kD) from L. japonica was fermented, the pH in fecal cultures decreased from 6.5 to 5.1 and the levels of short chain fatty acids, such as acetic, butyric and lactic acids all significantly increased. After 48 h fermentation, 0.8 g MWCOL showed good effect on modulating the gut microflora balance, because the beneficial strains (Lactobacillus and Bifidobacterium) were both significantly higher than those in control group (p < 0.05). As far as we know, this is the first report that consumption of sulfated polysaccharides from E. prolifera and L. japonica is beneficial to the ecosystem of the intestinal tract by increasing the populations of probiotics and short chain fatty acids. Furthermore, our reports indicated that molecular weight of sulfated polysaccharide from marine algae is related to its prebiotic effects.