Oral delivery of anticancer drugs III: formulation using drug delivery systems

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• 作者：Silvia Mazzaferro ; Kawthar Bouchemal ; ^{kawthar.bouchemal@u-psud.fr} ; Gilles Ponchel
• 刊名：Drug Discovery Today
• 出版年：2013
• 出版时间：January, 2013
• 年：2013
• 卷：18
• 期：1-2
• 页码：99-104
• 全文大小：198 K

文摘

In the past few years, the growth of nanometric size drug delivery systems (DDS) has burst into challenging innovations enabling real progresses to achieve oral delivery of anticancer drugs. DDS, such as polymeric nanoparticles, micelles, dendrimers and lipid-based formulations enable physico-chemical properties of cytotoxic agents to be improved and oral bioavailability to be enhanced. In this review we highlight current DDS used for the oral delivery of anticancer drugs.